Dwayne Johnson and his giant ape friend are ready to take on the monsters in this second trailer for Rampage, a big-screen adaptation of the popular 1980s video game.

Johnson plays Davis Okoye, a primatologist who has been looking after a silverback gorilla named George since the animal was young. But then a rogue experiment turns the gorilla into a giant, along with several other animals, including a wolf and a crocodile – as they destroy everything in their path. It’s up to Davis, with the help of George, to try and stop the animals – and the government baddies who created them. It also stars Naomie Harris, Malin Akerman, Jake Lacy, Joe Manganiello, and Jeffrey Dean Morgan.

Watch the trailer!

Rampage opens in theaters April 20.